Baylor Research Institute
Programs
Baylor Scott & White Research Institute Programs
See Schedule OEstablished in 1984, Baylor Scott & White Research Institute (BSWRI) is responsible for the oversight and management of all translational, observational, and clinical research conducted throughout the Baylor Scott & White Health (BSWH) system. BSWRI expanded its operations in 2013 as part of the merger between Dallas-based Baylor Health Care System and Temple-based Scott & White Healthcare, which created BSWH the largest nonprofit health system in Texas. Today, BSWH has over 1,100 patient access points including 51 hospitals, 561 specialty care clinics, 195 outpatient clinics, 160 primary care clinics, 32 pharmacies, 29 ambulatory surgery centers, and more than 7,300 active physicians. The system also includes a state certified health maintenance organization, the Scott and White Health Plan and the Baylor Scott & White Quality Alliance accountable care organization both covering over 983,000 lives. BSWRI brings innovation to the forefront of medicine. From contributing to discoveries that help create new treatment options, to studying population health and other trends that improve quality of care, we pursue research focused on bringing patients greater value and addressing the health needs of the communities we serve. We are dedicated to advancing healthcare and ultimately, patient care, through the study and discovery of new preventive therapies and treatments for a broad spectrum of diseases and other chronic conditions. This means our efforts extend beyond microscopic studies; they bring innovation to the patient's bedside. We focus on understanding the base of a disease or condition, in order to then identify potential treatments or preventive therapies and enroll patients in research trials to further test and/or validate each theory. BSWRI is accredited by the Association for the Accreditation of Human Research Protection Programs (AAHRPP), which is a voluntary, peer-driven, and education-based model of accreditation.BSWRI is home to a rich network of 1,000 team members operating within two administrative offices (Dallas and Temple), four clinical trials offices (Dallas, Fort Worth, Plano and Temple) and directly within various BSWRI centers, hospitals and clinics. Research staff include principal investigators, contracts and finance specialists, compliance and regulatory specialists, research coordinators, nurses, managers, data analysts and lab assistants, among others. The group oversees research activities supporting nearly 1,800 trials in more than 50 specialty areas annually, including infectious disease, cardiology, gastroenterology, trauma, rehabilitation, neurology, oncology and radiation, orthopedics, pathology, radiology, transplant and surgery. Research conducted by and supported by our organization is regularly published in major scientific journals and reported at medical and scientific meetings. This work has also resulted in more than 500 issued and pending patents and trademark registrations spanning immunotherapy, genomics, biomarkers, metabolomics, metabolics, cardiovascular disease and medical devices. The following is a brief snapshot of activities led through BSWRI:Cardiovascular research: BSWRI holds a robust cardiovascular portfolio with study enrollment activities spanning multiple BSWH sites. Each year, we enroll and monitor hundreds of patients as part of major clinical trials examining therapeutic and surgical approaches and outcomes, new medications and new devices. Our cardiovascular research portfolio supports trials spanning: Atrial Fibrillation, Vascular/TAA conditions, Heart Failure Transplant, Heart Rhythm Disorders, Hypercholesterolemia, Aortic Valve Disorders, Cardiorenal Syndrome, Electrophysiology, Coronary Artery Disease, & Mitral Valve Disorders.Oncology research: BSWH treats a sizeable population with clinical care and research closely integrated into the options available to cancer patients. Our research teams support oncology trials at multiple sites, including Baylor Scott & White Cancer Center-Round Rock, Baylor Scott & White Medical Center - Temple, Baylor Scott & White McClinton Cancer Center Waco, Baylor Scott & White McLane Children's Hospital, and Baylor Scott & White Charles A. Sammons Cancer Centers. BSWRI conducts research aimed at advancing the knowledge around screenings, prevention, diagnostic, and treatment options We run multiple trials across BSWH, including cutting-edge first-in-human CAR-T cell, dendritic vaccine, and Phase I, II and III studies for a broad number of malignancies. Applied health research: The Center for Applied Health Research (CAHR) is a collaborative, multidisciplinary research center that brings together clinicians, educators and researchers with expertise in areas such as health services research, administrative data extraction and reduction, derivation of care and outcome measures from archival medical records, community-based health research, statistical analysis, research mentoring, patient-centered safety, patient activation research and academic development of clinicians. CAHR efforts focus on the development and testing of innovations care models within healthcare and community settings, studying the impact of health programs on population health. Current CAHR programs include: 1) development and testing of innovative care models within health care and community settings, 2) impact of care delivery on the health and well-being of individuals and families, and 3) major projects designed to address the needs of aging populations and their caregivers. Our diverse research programs demonstrate collaborative efforts with various organizations, including the Department of Veterans Affairs, Texas A&M Health Science Center, national foundations and numerous health-oriented community-based organizations across Texas. Trauma and behavioral health research: BSWRI supports trauma and behavioral health research across multiple sites. Through the Trauma Research Consortium, our research efforts in addressing physical, mental and emotional trauma have been brought together under a single umbrella in order to enhance our ability to combine resources, inform best practices and further expand our ability to share our learnings out to others. One example of this work is found in the Warriors Research Institute (WRI). WRI's mission is to improve the quality of care available to military veterans and emergency responders via a program of scientific inquiry. Through BSWRI, WRI develops, evaluates, and disseminates information about treatment models for those suffering the sequelae of toxic or traumatic work events. In addition to providing and evaluating state-of-the-art experimental treatments, we train future generations of treatment providers in evolving evidence-based care. WRI leaders continue to foster WRI's growth beyond traditional research programs by also mentoring staff and volunteers, serving on multiple boards, committees, and panels, and consulting for the International Association of Firefighters (IAFF) and the National Development and Research Institutes (NDRI).Transplant research: Our research efforts around transplantation take place at multiple sites including Baylor University Medical Center and Baylor Scott & White Medical Center - Temple. This research continues to hit major milestones and research firsts. BSWRI supports multiple trials examining transplant procedures and post-op care, as well as addressing transplant waitlists and organ shortages. Our efforts in the specialty of abdominal transplant, as well as heart and lung transplants, continue to support efforts to improve outcomes, inform access to organs, and educate medical staff on best practices. These include an investigator-initiated studies examining issues such as the global burden of alcohol- associated liver disease and the impact of new acuity circle policies for liver allocation. This work also extends to studies examining new artificial heart technologies for individuals needing a heart transplant.COVID Research: As part of its continued response to the COVID-19 pandemic, BSWRI has maintained an active portfolio of laboratory-based and data collection studies, as well as clinical drug and therapy trials to investigate transmission prevention, diagnosis, and treatment options for mild, moderate and severe COVID cases. Additionally, BSWRI has been actively involved in studies designed to assess the vaccine efficacy amongst vaccinated populations. To date more than 50 COVID-related studies and research projects have been supported by BSWRI with more than 11,000 participants.GeographiesNot indicatedDatesJul 1, 2020 – Jun 30, 2021Source990No causes providedNo populations provided–$56.9MProgram 1 [2024]
See Schedule OEstablished in 1984, Baylor Scott & White Research Institute (BSWRI) is responsible for the oversight and management of all translational, observational, and clinical research conducted throughout the Baylor Scott & White Health (BSWH) system. BSWRI expanded its operations in 2013 as part of the merger between Dallas-based Baylor Health Care System and Temple-based Scott & White Healthcare, which created BSWH the largest nonprofit health system in Texas. Today, BSWH has over 1,300 patient access points including 52 hospitals, 632 specialty care clinics, 260 outpatient clinics, 164 primary care clinics, 29 pharmacies, 30 ambulatory surgery centers, 62 urgent care clinics, and more than 7,200 active physicians. The system also includes a state certified health maintenance organization, the Scott and White Health Plan and the Baylor Scott & White Quality Alliance accountable care organization both covering over 1,200,000 lives. BSWRI brings innovation to the forefront of medicine. From contributing to discoveries that help create new treatment options, to studying population health and other trends that improve quality of care, we pursue research focused on bringing patients greater value and addressing the health needs of the communities we serve. We are dedicated to advancing healthcare and ultimately, patient care, through the study and discovery of new preventive therapies and treatments for a broad spectrum of diseases and other chronic conditions. This means our efforts extend beyond microscopic studies; they bring innovation to the patient's bedside. We focus on understanding the base of a disease or condition, in order to then identify potential treatments or preventive therapies and enroll patients in research trials to further test and/or validate each theory. BSWRI is accredited by the Association for the Accreditation of Human Research Protection Programs (AAHRPP), which is a voluntary, peer-driven, and education-based model of accreditation.BSWRI is home to a rich network of over 600 team members operating within two administrative offices, four clinical trials offices, and directly within various BSWH centers, hospitals and clinics. Research staff include principal investigators, contracts and finance specialists, compliance and regulatory specialists, research coordinators, nurses, managers, data analysts and lab assistants, among others. The group oversees research activities supporting nearly 1,400 studies in more than 50 specialty areas annually, including infectious disease, cardiology, gastroenterology, trauma, rehabilitation, neurology, oncology and radiation, orthopedics, pathology, radiology, transplant and surgery. Research conducted by and supported by our organization is regularly published in major scientific journals and reported at medical and scientific meetings. This work has also resulted in more than 1,600 issued and pending patents and trademark registrations spanning immunotherapy, genomics, biomarkers, metabolomics, metabolics, cardiovascular disease and medical devices. The following is a brief snapshot of activities led through BSWRI:Cardiovascular research: BSWRI holds a robust cardiovascular portfolio with study enrollment activities spanning multiple BSWH sites. Each year, we enroll and monitor hundreds of patients as part of major clinical trials examining therapeutic and surgical approaches and outcomes, new medications and new devices. Our cardiovascular research portfolio supports trials spanning: Atrial Fibrillation, Vascular/TAA conditions, Heart Failure Transplant, Heart Rhythm Disorders, Hypercholesterolemia, Aortic Valve Disorders, Cardiorenal Syndrome, Electrophysiology, Coronary Artery Disease, & Mitral Valve Disorders.Oncology research: In 2020, the Texas Immuno-Oncology Biorepository (TIOB) was created, a state-wide multispecialty biorepository housed at 8 research sites across North and Central Texas. BSWH treats a sizeable population with clinical care and research closely integrated into the options available to cancer patients. Our research teams support oncology trials at multiple sites. BSWRI conducts research aimed at advancing the knowledge around screenings, prevention, diagnostic, and treatment options. We run multiple trials across BSWH, including cutting-edge first-in-human CAR-T cell, dendritic vaccine, and Phase I, II and III studies for a broad number of malignancies.The Center for Applied Health Research (CAHR) supports competitively funded investigator-initiated research to generate applied health knowledge across our health care system.It is a multidisciplinary, system-level research center within the Baylor Scott & White Research Institute (BSWRI) and serves as a collaborative for researchers, clinicians and community leaders who seek to improve health care delivery and health outcomes. The core value of CAHR is to support innovations that lead to improve outcomes and the value of care for our patients and community. We are located in Temple and Dallas, Texas.CAHR's research programs include: (1) Intervention development of community and family support programs for persons with dementia and their family caregivers (2) Implementation science of evidence-based programs leading to innovations in care delivery (3) Dissemination of evidence-based programs/practices for older adults from diverse settings (4) Healthcare delivery implementation programs to address critical illness outside of the ICU (5) Intervention development to support patients and families after critical illness and (6) Real-world clinical and economic evidence generation focused on drug therapy outcomes in ambulatory care.Trauma and behavioral health research: BSWRI supports trauma and behavioral health research across multiple sites and departments. Our research investigators take a collaborative and multidisciplinary approach to address physical, mental, and emotional trauma, which enhances ability to combine resources, inform best practices and further expand our ability to share our learnings out to others. One example of this work is found in the Warriors Research Institute (WRI). WRI's mission is to improve the quality of care available to military veterans and emergency responders via a program of scientific inquiry. Through BSWRI, WRI develops, evaluates, and disseminates information about treatment models for those suffering the sequelae of toxic or traumatic work events. In addition to providing and evaluating state-of-the-art experimental treatments, we train future generations of treatment providers in evolving evidence-based care. A second example is with the work done by the Trauma Research Center and Behavioral Health departments. These teams bring together the efforts of experienced researchers whose research focuses on trauma and related conditions resulting from a variety of etiologies including life events and the psychological conditions resulting from trauma. These researchers work closely with the trauma centers and rehabilitation teams at BSWH as well as external trauma centers across the country. They also study the psychological impacts of trauma-exposed occupational populations, such as healthcare personnel and active-duty service members.Transplant research: Our research efforts around transplantation take place at multiple sites including Baylor Scott & White All Saints Medical Center - Fort Worth, Baylor University Medical Center and Baylor Scott & White Medical Center - Temple. This research continues to hit major milestones and research firsts. BSWRI supports multiple trials examining transplant procedures and post-op care, as well as addressing transplant waitlists and organ shortages. Our efforts in the specialty of abdominal transplant, as well as heart and lung transplants, continue to support efforts to improve outcomes, inform access to organs, and educate medical staff on best practices. These include an investigator-initiated studies examining issues such as the global burden of alcohol-associated liver disease and the impact of new acuity circle policies for liver allocation. This work also extends to studies examining new artificial heart technologies for individuals needing a heart transplant.GeographiesNot indicatedDatesJul 1, 2023 – Jun 30, 2024Source990No causes providedNo populations provided–$69.1M
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